Skip to main navigation Skip to main content

CEEM : Clinical and Experimental Emergency Medicine

OPEN ACCESS
Search
Advanced Search
ABOUT
BROWSE ARTICLES
FOR CONTRIBUTORS

Page Path

8
results for

"Dong Hyuk Shin"

Article category

Publication year

More +

Keywords

"Dong Hyuk Shin"

Original Articles

Cardiovascular | Imaging

Can left atrial diameter measured by computed tomography predict the presence and degree of left ventricular diastolic dysfunction?
Gae An Kim, Ji Ung Na, Dong Hyuk Shin, Jang Hee Lee
Clin Exp Emerg Med 2024;11(4):358-364.   Published online May 23, 2024
DOI: https://doi.org/10.15441/ceem.24.194

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

Can left atrial diameter measured by computed tomography predict the presence and degree of left ventricular diastolic dysfunction?
Clin Exp Emerg Med. 2024;11(4):358-364.   Published online May 23, 2024
DOI: https://doi.org/10.15441/ceem.24.194
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
Can left atrial diameter measured by computed tomography predict the presence and degree of left ventricular diastolic dysfunction?
Clin Exp Emerg Med. 2024;11(4):358-364.   Published online May 23, 2024
DOI: https://doi.org/10.15441/ceem.24.194
Close
Objective
This study was conducted to determine whether the presence and degree of left ventricular diastolic dysfunction (LVDD) can be predicted by the simple computed tomography -measured left atrial diameter (CTLAD). Methods Among adult patients who underwent both chest CT imaging and echocardiography in the emergency department from January 2020 to December 2021, a retrospective cross-sectional study enrolled patients in whom the time interval between the two tests was <24 hours. Receiver operating characteristic (ROC) curve analysis was used to evaluate the diagnostic power of CTLAD for echocardiographic LVDD. Results In a study involving 373 patients, 192 (51.5%) had LVDD. Among them, 122 (63.5%) had grade 1, 61 (31.8%) had grade 2, and nine (4.7%) had ≥grade 3. Median CTLAD values were 4.1 cm for grade 1, 4.5 cm for grade 2, and 4.9 cm for ≥grade 3. The area under the ROC curve value of CTLAD in distinguishing ≥grade 1, ≥grade 2 (optimal cutoff ≥4.4 cm), and ≥grade 3 (optimal cutoff ≥4.5 cm) were 0.588, 0.657 (sensitivity, 61.4%; specificity, 66.0%, positive predictive value, 29.5%; negative predictive value, 88.1%; odds ratio, 3.1), and 0.834 (sensitivity, 88.9%; specificity, 70.1%; positive predictive value, 6.8%; negative predictive value, 99.6%, odds ratio, 18.7), respectively. Conclusion CTLAD ≥4.4 cm can be used as a rough reference value to distinguish LVDD of ≥grade 2, while CTLAD ≥4.5 cm can reliably distinguish LVDD of ≥grade 3. CTLAD might be a useful parameter for predicting LVDD in situations where echocardiography is not available.

Citations

Citations to this article as recorded by  Crossref logo
  • Development and validation of a predictive model for cancer therapy-related cardiac dysfunction in breast cancer patients using echocardiographic indicators
    Shan Hui
    American Journal of Cancer Research.2025; 15(5): 2243.     CrossRef
  • 4,643 View
  • 72 Download
  • 1 Crossref

Imaging | Cardiovascular

A study on computed tomography cardiothoracic ratio in predicting left ventricular systolic dysfunction
Minki Chae, Ji Ung Na, Jang Hee Lee, Dong Hyuk Shin
Clin Exp Emerg Med 2023;10(1):52-59.   Published online February 14, 2023
DOI: https://doi.org/10.15441/ceem.22.382

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

A study on computed tomography cardiothoracic ratio in predicting left ventricular systolic dysfunction
Clin Exp Emerg Med. 2023;10(1):52-59.   Published online February 14, 2023
DOI: https://doi.org/10.15441/ceem.22.382
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
A study on computed tomography cardiothoracic ratio in predicting left ventricular systolic dysfunction
Clin Exp Emerg Med. 2023;10(1):52-59.   Published online February 14, 2023
DOI: https://doi.org/10.15441/ceem.22.382
Close
Objective
A cardiothoracic ratio ≥0.50 is widely used as an indicator of cardiomegaly, but associations between the cardiothoracic ratio and left ventricular systolic dysfunction (LVSD) have not been investigated previously. We conducted this study to investigate the relationship between cardiothoracic ratio measured using computed tomography (CT) and left ventricular ejection fraction (LVEF), and to determine the optimal cardiothoracic ratio for predicting left ventricular systolic dysfunction (LVSD).
Methods
A retrospective cross-sectional study was performed using data from patients who underwent both chest CT and echocardiography at the emergency department from January 1 to December 31, 2021. The patients were classified as normal, or having mild, moderate, and severe LVSD based on their LVEF, and the cardiothoracic ratios of each group were compared. The receiver operating characteristic (ROC) curve analyses were used to identify the optimal cardiothoracic ratio for prediction of mild, moderate, and severe LVSD.
Results
The final study population included 444 patients. The median CT-measured cardiothoracic ratio was 0.54 for patients with normal LVEF, and 0.60 for patients with LVSD (P<0.001). The optimal CT-measured cardiothoracic ratios for predicting mild, moderate, and severe LVSD were 0.56, 0.59, and 0.60, and their areas under the ROC curve were 0.653, 0.690, and 0.680, and negative predictive values were 90%, 94%, and 98%, respectively.
Conclusion
The best cutoff value for a CT-measured cardiothoracic ratio suggestive of LVSD was 0.56, which is very different from the 0.50 value typically considered an abnormal cardiothoracic ratio. The CT-measured cardiothoracic ratio ≥0.56 can be used as a rough indicator of mild LVSD, and a ratio <0.60 can exclude severe LVSD with a high degree of confidence.

Citations

Citations to this article as recorded by  Crossref logo
  • Comparison of Deep Learning Architectures for Cardiac Contour Segmentation in Catheterization Radiographs
    Kian A Huang, Bharath Subramanian, Haris K Choudhary, Aziz U Rehman, Neelesh S Prakash
    Cureus.2026;[Epub]     CrossRef
  • Association of artificial intelligence derived cardiothoracic ratio assessment on non-cardiac chest CT with heart failure and all-cause mortality: A retrospective single center study
    John LaForge, Ahmed Saleh, Vibhu Parcha, Akhilesh Gonuguntla, Shrikar Iragavarapu, Salomón Román Soto, Usman A. Hasnie, Gina Josey, Megan Nordberg, Andrew Smith, Steven Rothenberg, Stephen A. Clarkson
    The American Journal of the Medical Sciences.2026; 372(1): 27.     CrossRef
  • Analysis of non-coronary findings in coronary CT angiography: differences in gender, age, location, and clinical significance in the Turkish population
    Muhammet İkbal Isik, Mustafa Taşar
    RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren.2026;[Epub]     CrossRef
  • Predictors of echocardiographic abnormalities in asymptomatic individuals with increased cardiothoracic ratio detected on chest radiography
    Narongchai Wattanawongwon, Arjbordin Winijkul, Nithima Ratanasit, Kamol Udol
    American Heart Journal Plus: Cardiology Research and Practice.2026; 69: 100848.     CrossRef
  • Heart size on chest CT and its association with acute heart failure in the emergency department
    Emilie Melgaard, Lucas Malta Westergaard, Anne Sophie Olesen, Kristina Miger, Sandra Tonning, Silas Nyboe Ørting, Jens Petersen, Olav Wendelboe Nielsen, Johannes Grand
    Danish Medical Journal.2026; : 1.     CrossRef
  • Novel Indexes in the Assessment of Cardiac Enlargement Using Chest Radiography: A New Look at an Old Problem
    Patrycja S. Matusik, Tadeusz J. Popiela, Paweł T. Matusik
    Journal of Clinical Medicine.2025; 14(3): 942.     CrossRef
  • Systematic review and comparison of measurement methods for determining the cardiothoracic ratio (CTR) on chest X-rays with subsequent validation using chest CT
    Dana Belde, Mattias Kettner, Michael J. Thali, Rahel A. Kubik-Huch, André Euler, Tilo Niemann
    Medicine.2025; 104(40): e45062.     CrossRef
  • Radiologic evaluation of subclinical cardiovascular structural changes in school cafeteria workers: a chest computed tomography study with age-matched controls
    Jung Hee Hong, Jin Young Kim, Kiook Baek
    Journal of Yeungnam Medical Science.2025; 42: 76.     CrossRef
  • 19,091 View
  • 223 Download
  • 7 Web of Science
  • 8 Crossref
Clinical study on ureteritis observed in contrast-enhanced computed tomography in the emergency department
Jihyuk Chung, Ji Ung Na, Jang Hee Lee, Sang Kuk Han, Pil Cho Choi, Dong Hyuk Shin
Clin Exp Emerg Med 2022;9(3):216-223.   Published online August 4, 2022
DOI: https://doi.org/10.15441/ceem.21.152

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

Clinical study on ureteritis observed in contrast-enhanced computed tomography in the emergency department
Clin Exp Emerg Med. 2022;9(3):216-223.   Published online August 4, 2022
DOI: https://doi.org/10.15441/ceem.21.152
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
Clinical study on ureteritis observed in contrast-enhanced computed tomography in the emergency department
Clin Exp Emerg Med. 2022;9(3):216-223.   Published online August 4, 2022
DOI: https://doi.org/10.15441/ceem.21.152
Close
Objective
We aimed to investigate the causes and clinical and laboratory features of patients with ureteritis observed on intravenous contrast-enhanced abdominopelvic computed tomography (APCT) conducted in the emergency department (ED).
Methods
All APCTs conducted in the ED from November 2017 to November 2020 were investigated for the presence of ureteritis. The incidence of ureteritis, presumed cause of ureteritis, and clinical as well as laboratory features of patients with ureteritis were retrospectively analyzed.
Results
Ureteritis was observed in 422 out of 7,386 patients (5.7%) who underwent APCTs. The two main reasons for undergoing APCT in the ED were abdominal pain (49%) and infection focus workup (33%). The first major cause of ureteritis was urinary tract infection (UTI) (351 of 422, 83%). Most patients (85%) were febrile, but 208 (59%) exhibited no urinary symptoms such as dysuria, increased frequency, or residual urine sense. The second major cause of ureteritis was ureteral stones (42 of 422, 10%). Thirty-two of 42 patients (76%) had simple obstructive uropathy, while 24% of patients had a combined infection along with an obstruction. Other rare causes were malignancy and the spread of adjacent inflammation.
Conclusion
Ureteritis was a common finding observed in 5.7% of patients who underwent APCTs at the ED, and most of them were secondary to UTIs and ureteral stones. UTIs can cause ureteritis even without typical symptoms or signs suggestive of UTI, and diagnosis without an APCT can be difficult. More liberal use of APCTs should be considered when the cause of fever is difficult to diagnose.

Citations

Citations to this article as recorded by  Crossref logo
  • Hemolysis Control in the Emergency Department by Interventional Blood Sampling
    Hyeseung Lee, Heekyung Lee, Changsun Kim, Hyungoo Shin, Inhye Lee, Yihyun Kim
    Journal of Personalized Medicine.2023; 13(4): 651.     CrossRef
  • 11,871 View
  • 264 Download
  • 2 Web of Science
  • 1 Crossref

Neurology

Characteristics of blood tests in patients with acute cerebral infarction who developed symptomatic intracranial hemorrhage after intravenous administration of recombinant tissue plasminogen activator
Chungjo Lee, Ji Ung Na, Jang Hee Lee, Sang Kuk Han, Pil Cho Choi, Young Hwan Lee, Sang O Park, Dong Hyuk Shin
Clin Exp Emerg Med 2019;6(2):160-168.   Published online June 28, 2019
DOI: https://doi.org/10.15441/ceem.18.056

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

Characteristics of blood tests in patients with acute cerebral infarction who developed symptomatic intracranial hemorrhage after intravenous administration of recombinant tissue plasminogen activator
Clin Exp Emerg Med. 2019;6(2):160-168.   Published online June 28, 2019
DOI: https://doi.org/10.15441/ceem.18.056
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
Characteristics of blood tests in patients with acute cerebral infarction who developed symptomatic intracranial hemorrhage after intravenous administration of recombinant tissue plasminogen activator
Clin Exp Emerg Med. 2019;6(2):160-168.   Published online June 28, 2019
DOI: https://doi.org/10.15441/ceem.18.056
Close
Objective
Patients suspected as having acute ischemic stroke usually undergo blood tests, including coagulation-related indexes, because thrombocytopenia and coagulopathy are contraindications for recombinant tissue plasminogen activator (rtPA) administration. We aimed to identify blood test indexes associated with symptomatic intracranial hemorrhage (sICH) in patients with acute ischemic stroke who received intravenous rtPA.
Methods
This retrospective observational study included patients diagnosed with acute ischemic stroke who were treated with intravenous rtPA at the emergency department of a tertiary hospital in Seoul between February 2008 and January 2018. Blood test indexes were compared between the sICH and non-sICH groups. Logistic regression and receiver-operating characteristic curve analyses were performed.
Results
In this study, 375 patients were finally included. Of 375 patients, 42 (11.2%) showed new intracranial hemorrhage on follow-up brain computed tomography, of whom 14 (3.73%) had sICH. Platelet count, aspartate aminotransferase and lactate dehydrogenase levels were significantly different between the sICH and non-sICH groups, and platelet count showed statistical significance in the regression analysis. Significantly lower platelet counts were observed in the sICH group than in the non-sICH group (174,500 vs. 228,000/mm3, P=0.020). The best cutoff platelet count was 195,000/mm3, and patients with platelet counts of <195,000/mm3 had a 5.4- times higher risk of developing sICH than those with platelet counts of ≥195,000/mm3.
Conclusion
Platelet count was the only independent parameter associated with sICH among the blood test indexes. Mild thrombocytopenia may increase the risk of sICH after intravenous administration of rtPA.

Citations

Citations to this article as recorded by  Crossref logo
  • Insight of action mechanism of Astragaloside IV for relieving of cerebral ischemic injury in a rat model of middle cerebral artery occlusion reperfusion via proteomics and network pharmacology
    Xin-Hua Zhu, Xin Yu, Xiang-Wen Kong, Yi Zhang, Si-Liang Jiang, Jun-Hong Chai, Jun Liang, Hai-Xue Kuang, Yong-Gang Xia
    Journal of Natural Medicines.2025; 79(3): 591.     CrossRef
  • Risk factors of hemorrhagic transformation in acute ischaemic stroke: A systematic review and meta-analysis
    Jiacheng Sun, Christina Lam, Lauren Christie, Christopher Blair, Xingjuan Li, Freda Werdiger, Qing Yang, Andrew Bivard, Longting Lin, Mark Parsons
    Frontiers in Neurology.2023;[Epub]     CrossRef
  • 9,285 View
  • 136 Download
  • 3 Web of Science
  • 2 Crossref

Clinical Laboratory | Neurology

Hematologic parameters to predict negative cerebrospinal fluid examination results among neurologically intact patients who underwent lumbar puncture on suspicion of central nervous system infection
Ji Hwan Kim, Hong-Jik Kim, Ji Ung Na, Sang Kuk Han, Pil Cho Choi, Dong Hyuk Shin
Clin Exp Emerg Med 2017;4(1):25-31.   Published online March 30, 2017
DOI: https://doi.org/10.15441/ceem.16.152

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

Hematologic parameters to predict negative cerebrospinal fluid examination results among neurologically intact patients who underwent lumbar puncture on suspicion of central nervous system infection
Clin Exp Emerg Med. 2017;4(1):25-31.   Published online March 30, 2017
DOI: https://doi.org/10.15441/ceem.16.152
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
Hematologic parameters to predict negative cerebrospinal fluid examination results among neurologically intact patients who underwent lumbar puncture on suspicion of central nervous system infection
Clin Exp Emerg Med. 2017;4(1):25-31.   Published online March 30, 2017
DOI: https://doi.org/10.15441/ceem.16.152
Close
Objective
Cerebrospinal fluid (CSF) examination is mandatory whenever central nervous system (CNS) infection is suspected. However, pleocytosis is not detected in a substantial number of suspected patients who undergo CSF examination. This study aimed to identify parameters that can aid in predicting negative CSF examination results (defined as a white blood cell count of <5 cells/high-power field).
Methods
The study included 101 neurologically intact patients who underwent lumbar puncture because of suspicion of CNS infection. Patients were divided into negative and positive CSF examination groups, and their initial blood tests were comparatively analyzed.
Results
The negative group had a significantly higher proportion of neutrophils in white blood cells (81.5% vs. 75.8%, P=0.012), lower proportion of lymphocytes in white blood cells (9.3% vs. 16.7%, P=0.001), a higher neutrophil-to-lymphocyte ratio (9.1 vs. 4.4, P=0.001), a lower lymphocyte-to-monocyte ratio (1.6 vs. 2.4, P=0.008), and a higher C-reactive protein level (21.0 vs. 5.0 mg/L, P<0.001) than the positive group. In the receiver-operating characteristic analysis, neutrophil-to-lymphocyte ratio and C-reactive protein had an area under the curve of >0.7, and the best cutoff values were 6.0 (accuracy 70.3%) and 12.7 mg/L (accuracy 76.2%), respectively.
Conclusion
The neutrophil-to-lymphocyte ratio ≥6 and C-reactive protein level ≥12.7 mg/L was significantly associated with negative CSF examination result.

Citations

Citations to this article as recorded by  Crossref logo
  • Neutrophil-to-lymphocyte ratio as a feasible prognostic marker for pyogenic liver abscess in the emergency department
    Kwang Soon Park, Sun Hwa Lee, Seong Jong Yun, Seokyong Ryu, Keon Kim
    European Journal of Trauma and Emergency Surgery.2019; 45(2): 343.     CrossRef
  • 14,559 View
  • 138 Download
  • 3 Web of Science
  • 1 Crossref

Airway | Education & Simulation

Comparison of the GlideRite to the conventional malleable stylet for endotracheal intubation by the Macintosh laryngoscope: a simulation study using manikins
Yong Tack Kong, Hyun Jung Lee, Ji Ung Na, Dong Hyuk Shin, Sang Kuk Han, Jeong Hun Lee, Pil Cho Choi
Clin Exp Emerg Med 2016;3(1):9-15.   Published online March 31, 2016
DOI: https://doi.org/10.15441/ceem.15.038

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

Comparison of the GlideRite to the conventional malleable stylet for endotracheal intubation by the Macintosh laryngoscope: a simulation study using manikins
Clin Exp Emerg Med. 2016;3(1):9-15.   Published online March 31, 2016
DOI: https://doi.org/10.15441/ceem.15.038
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
Comparison of the GlideRite to the conventional malleable stylet for endotracheal intubation by the Macintosh laryngoscope: a simulation study using manikins
Clin Exp Emerg Med. 2016;3(1):9-15.   Published online March 31, 2016
DOI: https://doi.org/10.15441/ceem.15.038
Close
Objective
To compare the effectiveness of the GlideRite stylet with the conventional malleable stylet (CMS) in endotracheal intubation (ETI) by the Macintosh laryngoscope.
Methods
This study is a randomized, crossover, simulation study. Participants performed ETI using both the GlideRite stylet and the CMS in a normal airway model and a tongue edema model (simulated difficult airway resulting in lower percentage of glottic opening [POGO]).
Results
In both the normal and tongue edema models, all 36 participants successfully performed ETI with the two stylets on the first attempt. In the normal airway model, there was no difference in time required for ETI (TETI) or in ease of handling between the two stylets. In the tongue edema model, the TETI using the CMS increased as the POGO score decreased (POGO score was negatively correlated with TETI for the CMS, Spearman’s rho=-0.518, P=0.001); this difference was not seen with the GlideRite (rho=-0.208, P=0.224). The TETI was shorter with the GlideRite than with the CMS, however, this difference was not statistically significant (15.1 vs. 18.8 seconds, P=0.385). Ease of handling was superior with the GlideRite compared with the CMS (P=0.006).
Conclusion
Performance of the GlideRite and the CMS were not different in the normal airway model. However, in the simulated difficult airway model with a low POGO score, the GlideRite performed better than the CMS for direct laryngoscopic intubation.

Citations

Citations to this article as recorded by  Crossref logo
  • Association between glottis screen location and intubation difficulty: a retrospective video laryngoscopy study
    Kai-Yuan Cheng, Pang Hsu Liu, Yung-Cheng Su, Yen-Yu Chen, Ya-Ni Yeh, Jih-Chun Lin, Ming-Jen Tsai
    BMC Emergency Medicine.2024;[Epub]     CrossRef
  • 14,525 View
  • 138 Download
  • 4 Web of Science
  • 1 Crossref

Neurology | Imaging

Diffusion-weighted imaging–fluid-attenuated inversion recovery mismatch is associated with better neurologic response to intravenous thrombolytic therapy in acute ischemic stroke patients
Jong Yeong Jeong, Sang Kuk Han, Dong Hyuk Shin, Ji Ung Na, Hyun Jung Lee, Pil Cho Choi, Jeong Hun Lee
Clin Exp Emerg Med 2015;2(1):31-37.   Published online March 31, 2015
DOI: https://doi.org/10.15441/ceem.14.043

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

Diffusion-weighted imaging–fluid-attenuated inversion recovery mismatch is associated with better neurologic response to intravenous thrombolytic therapy in acute ischemic stroke patients
Clin Exp Emerg Med. 2015;2(1):31-37.   Published online March 31, 2015
DOI: https://doi.org/10.15441/ceem.14.043
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
Diffusion-weighted imaging–fluid-attenuated inversion recovery mismatch is associated with better neurologic response to intravenous thrombolytic therapy in acute ischemic stroke patients
Clin Exp Emerg Med. 2015;2(1):31-37.   Published online March 31, 2015
DOI: https://doi.org/10.15441/ceem.14.043
Close
Objective
To investigate differences in the effect of intravenous (IV) thrombolysis regarding the mismatch of diffusion-weighted imaging–fluid-attenuated inversion recovery (DWI-FLAIR) among acute ischemic stroke patients who visited the emergency department (ED) within 3 hours from the onset of symptoms.
Methods
Among ED patients presenting with an acute ischemic stroke between January 2011 and May 2013 at a tertiary hospital, those who underwent magnetic resonance imaging before IV thrombolytic therapy were included in this retrospective study. Patients were divided into DWI-FLAIR mismatch and match groups. National Institutes of Health Stroke Scale (NIHSS) scores obtained initially, 24 hours after thrombolytic therapy, and on discharge, and early neurologic improvement (ENI) and major neurologic improvement (MNI) were compared.
Results
During the study period, 50 of the 213 acute ischemic stroke patients who presented to the ED were included. The DWI-FLAIR mismatch group showed a statistically significantly greater reduction in NIHSS both at 24 hours after thrombolytic therapy and upon discharge than did the match group (5.5 vs. 1.2, P<0.001; 6.0 vs. 2.3, P<0.01, respectively). Moreover, ENI and MNI were significantly greater for the DWI-FLAIR mismatch group than for the match group (27/36 vs. 2/14, P<0.001; 12/36 vs. 0/14, P=0.012, respectively).
Conclusion
Among acute ischemic stroke patients who visited the ED within 3 hours from the onset of symptoms, patients who showed DWI-FLAIR mismatch showed a significantly better response to IV thrombolytic therapy than did the DWI-FLAIR match group in terms of neurologic outcome.

Citations

Citations to this article as recorded by  Crossref logo
  • Association of FLAIR Positivity and Worse Outcomes After Intravenous Thrombolysis in Known-Onset Strokes: A Systematic Review and Meta-Analysis
    Esra Zhubi, Azamat Bissenov, Anna Sára Lengyel, Réka Tóth, András Attila Horváth, Szabolcs Kéri, Marie Anne Engh, Péter Hegyi, Bence Gunda
    Journal of Clinical Medicine.2025; 14(22): 8031.     CrossRef
  • Fluid-Attenuated Inversion Recovery Hyperintense Ischemic Stroke Predicts Less Favorable 90-Day Outcome after Intravenous Thrombolysis
    Yongwoo Kim, Marie Luby, Nina-Serena Burkett, Gina Norato, Richard Leigh, Clinton B. Wright, Kyle C. Kern, Amie W. Hsia, John K. Lynch, Malik M. Adil, Lawrence L. Latour
    Cerebrovascular Diseases.2021; 50(6): 738.     CrossRef
  • 15,584 View
  • 135 Download
  • 2 Web of Science
  • 2 Crossref

Resuscitation

Early hyperoxemia may not increase mortality after cardiac arrest: a pilot study
Young Taeck Oh, Yong Hwan Kim, You Dong Sohn, Seung Min Park, Dong Hyuk Shin, Seong Youn Hwang, Suck Ju Cho, Sang O Park, Chong Kun Hong, Hee Cheol Ahn, Young Hwan Lee
Clin Exp Emerg Med 2014;1(1):28-34.   Published online September 30, 2014
DOI: https://doi.org/10.15441/ceem.14.017

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

Include:

Early hyperoxemia may not increase mortality after cardiac arrest: a pilot study
Clin Exp Emerg Med. 2014;1(1):28-34.   Published online September 30, 2014
DOI: https://doi.org/10.15441/ceem.14.017
Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
Format:
Include:
Early hyperoxemia may not increase mortality after cardiac arrest: a pilot study
Clin Exp Emerg Med. 2014;1(1):28-34.   Published online September 30, 2014
DOI: https://doi.org/10.15441/ceem.14.017
Close
Objective

International Liaison Committee on Resuscitation guidelines advocate an arterial saturation of 94% to 96% after return of spontaneous circulation (ROSC). However, a few clinical trials have investigated the impact of postresuscitative O2 therapy after cardiac arrest. We studied whether early hyperoxemia is associated with a poor post-ROSC outcome after in-hospital cardiac arrest.

 Methods

We retrospectively reviewed patients who experienced an in-hospital cardiac arrest from January 2005 to January 2011. Based on the results of the first arterial blood gas analysis (ABGA) within 10 minutes and a second ABGA from 60 to 120 minutes after ROSC, patients were classified into three groups: hyperoxemia (PaO2 ≥ 300 mmHg), normoxemia (300 mmHg > PaO2 ≥ 60 mmHg), and hypoxemia (PaO2 < 60 mmHg or ratio of PaO2 to fraction of inspired oxygen < 300). We examined whether early hyperoxemia was associated with survival and neurological outcome.

 Results

There were 792 patients who met the inclusion criteria: 638 (80.6%) in the hypoxemia group, 62 (7.8%) in the normoxemia group, and 92 (11.6%) in the hyperoxemia group. Multiple logistic regression analysis showed that hyperoxemia was not associated with survival (odds ratio [OR], 1.07; 95% confidence interval [CI], 0.30 to 3.84) or neurological outcome (OR, 1.03; 95% CI, 0.31 to 3.40).

 Conclusion

Postresuscitation hyperoxemia was not associated with survival or neurological outcome in patients with ROSC after in-hospital cardiac arrest.

Citations

Citations to this article as recorded by  Crossref logo
  • Neurological outcomes and mortality following hyperoxemia in adult patients with acute brain injury: an updated meta-analysis and meta-regression
    Nekane Romero-Garcia, Chiara Robba, Berta Monleón, Ana Ruiz-Zarco, Maria Pascual-González, Alberto Ruiz-Pacheco, Felipe Perdomo, Maria Luisa García-Pérez, Ana Mugarra, Laura García, Jose Carbonell, Lavienraj Premraj, Fabio Silvio Taccone, Rafael Badenes
    Critical Care.2025;[Epub]     CrossRef
  • Early restricted oxygen therapy after resuscitation from cardiac arrest (ER-OXYTRAC): protocol for a stepped-wedge cluster randomised controlled trial
    Ryo Yamamoto, Kazuma Yamakawa, Akira Endo, Koichiro Homma, Yasunori Sato, Ryo Takemura, Takeshi Yamagiwa, Keiki Shimizu, Daiki Kaito, Masayuki Yagi, Taku Yonemura, Takayuki Shibusawa, Ginga Suzuki, Takahiro Shoji, Naoya Miura, Jiro Takahashi, Chihiro Nari
    BMJ Open.2023; 13(9): e074475.     CrossRef
  • Restrictive versus high-dose oxygenation strategy in post-arrest management following adult non-traumatic cardiac arrest: a meta-analysis
    S. Macherey-Meyer, S. Heyne, M. M. Meertens, S. Braumann, C. Hueser, V. Mauri, S. Baldus, S. Lee, C. Adler
    Critical Care.2023;[Epub]     CrossRef
  • Monitoring of cerebral oxygenation during cardiopulmonary resuscitation may dramatically reduce the incidence of severe hyperoxia
    Filippo Sanfilippo, Luigi La Via, Veronica Dezio, Marinella Astuto, Alberto Morgana
    Resuscitation.2022; 170: 363.     CrossRef
  • The Effect of Hyperoxemia on Neurological Outcomes of Adult Patients: A Systematic Review and Meta-Analysis
    Chanawee Hirunpattarasilp, Hiroko Shiina, Nat Na-Ek, David Attwell
    Neurocritical Care.2022; 36(3): 1027.     CrossRef
  • Supranormal arterial oxygen tension only during the first six hours after cardiac arrest is associated with unfavourable outcomes
    Hyoung Youn Lee, Yong Hun Jung, Kyung Woon Jeung, Eul Noh, Jiho Lee, Jung Chul Kim, Byung Kook Lee, Tag Heo, Yong Il Min
    Acta Anaesthesiologica Scandinavica.2022; 66(10): 1247.     CrossRef
  • Attempting to prevent hyperoxaemia after out-of-hospital resuscitation
    Natalie Scotney
    Journal of Paramedic Practice.2022; 14(10): 402.     CrossRef
  • The effects of exposure to severe hyperoxemia on neurological outcome and mortality after cardiac arrest
    Luigi LA VIA, Marinella ASTUTO, Elena G. BIGNAMI, Diana BUSALACCHI, Veronica DEZIO, Massimo GIRARDIS, Bruno LANZAFAME, Giuseppe RISTAGNO, Paolo PELOSI, Filippo SANFILIPPO
    Minerva Anestesiologica.2022;[Epub]     CrossRef
  • Ventilation During Cardiac Arrest and After Return of Spontaneous Circulation: Like Father, Like Son?
    Johannes Wittig, Simon Orlob, Gerhard Prause
    Respiratory Care.2021; 66(3): 538.     CrossRef
  • Mechanical Ventilation Management During Mechanical Chest Compressions
    Daniele Orso, Luigi Vetrugno, Nicola Federici, Matteo Borselli, Savino Spadaro, Gianmaria Cammarota, Tiziana Bove
    Respiratory Care.2021; 66(2): 334.     CrossRef
  • Ventilation During Cardiac Arrest and After Return of Spontaneous Circulation: More than a Family Affair . . . the Truth Will Be in the Details
    Daniele Orso, Luigi Vetrugno, Tiziana Bove
    Respiratory Care.2021; 66(3): 539.     CrossRef
  • Oxygenation and ventilation targets after cardiac arrest: A systematic review and meta-analysis
    Mathias J. Holmberg, Tonia Nicholson, Jerry P. Nolan, Steve Schexnayder, Joshua Reynolds, Kevin Nation, Michelle Welsford, Peter Morley, Jasmeet Soar, Katherine M. Berg
    Resuscitation.2020; 152: 107.     CrossRef
  • Oxygen administration in patients recovering from cardiac arrest: a narrative review
    Ryo Yamamoto, Jo Yoshizawa
    Journal of Intensive Care.2020;[Epub]     CrossRef
  • Effects of the duration of postresuscitation hyperoxic ventilation on neurological outcome and survival in an asphyxial cardiac arrest rat model
    Tongyi Hu, Jianjie Wang, Shuangwei Wang, Jingru Li, Bihua Chen, Feng Zuo, Lei Zhang, Yuanyuan Huang, Yongqin Li
    Scientific Reports.2019;[Epub]     CrossRef
  • Association between intra- and post-arrest hyperoxia on mortality in adults with cardiac arrest: A systematic review and meta-analysis
    Jignesh K. Patel, Abdo Kataya, Puja B. Parikh
    Resuscitation.2018; 127: 83.     CrossRef
  • 17,070 View
  • 85 Download
  • 17 Web of Science
  • 15 Crossref
First First Prev Prev
Page of 1
Next Next Last Last
CEEM : Clinical and Experimental Emergency Medicine