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"Drug overdose"

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A fatal case of acute bentazone overdose despite cricothyroidotomy during cardiopulmonary resuscitation
Clin Exp Emerg Med. 2017;4(4):254-257.   Published online October 20, 2017
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A fatal case of acute bentazone overdose despite cricothyroidotomy during cardiopulmonary resuscitation
Clin Exp Emerg Med. 2017;4(4):254-257.   Published online October 20, 2017
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Bentazone is classified as a moderately hazardous (class II) herbicide by the World Health Organization. A 53-year-old Korean woman was transferred to the emergency department after a suicide attempt using approximately 500 mL of bentazone one hour prior to admission. Upon admission, she was alert and tachycardia of 125/min was observed. She was treated with gastric lavage and activated charcoal, during which she experienced diarrhea. Two hours after bentazone ingestion, cardiac arrest and muscle rigidity throughout the body occurred. Cardiopulmonary resuscitation was immediately started. Endotracheal intubation after administration of a muscle relaxant (succinylcholine) was unsuccessful because of temporomandibular joint muscle rigidity. Surgical cricothyroidotomy was performed by the emergency physician, but the patient was not resuscitated. For cardiac arrest patients with muscle rigidity caused by bentazone overdose, endotracheal intubation may be challenging because of muscle rigidity, despite appropriate use of muscle relaxants. Early surgical cricothyroidotomy may be the preferred method of airway management in these patients.

Citations

Citations to this article as recorded by  Crossref logo
  • Mortality due to minimal bentazone intoxication: a case report
    Yumin Jeon, Sejoong Ahn, Jong-Hak Park, Hanjin Cho, Sungwoo Moon, Sukyo Lee
    Clinical and Experimental Emergency Medicine.2026; 13(1): 86.     CrossRef
  • A narrative review of contemporary lethal pesticides: unveiling the ongoing threat of pesticide poisoning
    Sangchun Choi, Gi Woon Kim, Hoon Lim
    Clinical and Experimental Emergency Medicine.2024; 11(4): 335.     CrossRef
  • Bentazone in water and human urine in Wuhan, central China: exposure assessment
    Pei Wang, Meiling Cao, Feng Pan, Junling Liu, Yanjian Wan, Huaiji Wang, Wei Xia
    Environmental Science and Pollution Research.2022; 29(5): 7089.     CrossRef
  • 10,194 View
  • 184 Download
  • 3 Web of Science
  • 3 Crossref
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Accuracy of tablet counts estimated by members of the public and healthcare professionals
Clin Exp Emerg Med. 2015;2(3):168-173.   Published online September 30, 2015
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Accuracy of tablet counts estimated by members of the public and healthcare professionals
Clin Exp Emerg Med. 2015;2(3):168-173.   Published online September 30, 2015
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Objective
Intentional and accidental drug intoxication is commonly seen in the emergency department. When treating intoxicated patients, accessing the amount of the ingested drug is crucial albeit often difficult. We investigated the accuracy of estimating tablet counts when participants were asked to hold tablets in their fists and hands (semi-quantitative terms).
Methods
The widths and lengths of the participants’ hands were measured. Then, the subjects were asked to hold 5-mm round, 10-mm round, 10-mm oval, and 15-mm elliptical tablets using their hands and fists and to estimate the number of tablets they were holding. Differences between the estimated and actual numbers of tablets were examined.
Results
A total of 47 members of the public and 32 healthcare professionals were included in our study. In our analyses of the differences between the actual and estimated amounts of tablets held in the participants’ hands and fists, we found that the actual amount was higher than the estimated amount for all tablet types and in both groups. When participants held the tablets in the same manner (handful or fistful), the differences between the actual and estimated amounts were greater for 5- than 15-mm-sized tablets (P<0.05).
Conclusion
The treatment of patients presenting with drug overdoses to the emergency department should be based on the assumption that the actual amount of drugs the patients ingested is likely greater than the amount the patients state.

Citations

Citations to this article as recorded by  Crossref logo
  • Oral potassium poisoning: a retrospective review of the National Poison Data System 2010–2021
    Rita Farah, Joseph E. Carpenter, Brent W. Morgan
    Clinical Toxicology.2024; 62(1): 46.     CrossRef
  • 22,776 View
  • 80 Download
  • 2 Web of Science
  • 1 Crossref