Purple urine bag syndrome (PUBS) is a discoloration of urine generally seen in patients with UTI. Predisposing patient factors include advanced age, long-term urinary catheterization, chronic kidney disease, increased dietary intake of tryptophan, alkaline urine, concurrent constipation, and ileus [1,2]. Bacteria that are implicated in its development include Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae, and Pseudomonas aeruginosa [3]. PUBS is a benign condition that can occur when these gram-negative bacteria in urine convert tryptophan derivatives into pigmented metabolites. The derivative, indoxyl sulfate, is secreted into the urine where the sulfatases and phosphatases convert it into its two metabolites: indigo (a blue pigment) and indirubin (a red pigment) [2]. As these pigments interact with tubing of the Foley bag, a characteristically rare purple hue is produced. While isolated PUBS can be a benign finding, it may be associated with increased patient mortality and should alert the provider to investigate for underlying infection [3].