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Review Article 2024 September 6
Applications of ocular point-of-care ultrasound assessment in the emergency setting: a scoping review
Objective: To evaluate the current body of literature pertaining to the use of ocular point-of-care ultrasound (POCUS) in the emergency department (ED). Methods: A comprehensive literature search was conducted on Scopus, Web of Science, MEDLINE, and Cochrane Central Register of...
Review Article 2025 January 14
The landscape of experimental cardiac arrest research models in rats: a bibliometric analysis of the 100 most cited articles
This bibliometric analysis of the 100 most cited articles on experimental cardiac arrest models in rats identifies key contributors, publication trends, research themes, and collaboration networks. A comprehensive literature search of the Web of Science database was performed on...
Systematic Review 2025 January 14
Comparison of 4-factor fixed-dose versus 4-factor weight-based–dose prothrombin complex concentrate for emergent warfarin reversal: a systematic review and meta-analysis
Objective: The objective of this systematic review and meta-analysis is to evaluate the efficacy, safety, time to international normalized ratio (INR) reversal, and total volume of four-factor prothrombin complex concentrate (4-PCC) administered using fixed-dose versus weight-ba...
Original Article 2025 January 15
Derivation and validation of a simple prognostic risk score to predict short-term mortality in acute cardiogenic pulmonary edema: the SABIHA score
Objective: Acute cardiogenic pulmonary edema (ACPE) is a frequently encountered medical emergency associated with high early mortality rates, but existing tools to predict short-term outcomes for risk stratification have several limitations. Our aim was to derive and validate a ...
Original Article 2025 April 30
Interethnic validation of electrocardiogram image analysis software for detecting left ventricular dysfunction in an emergency department population
Objective: We previously developed and validated an artificial intelligence-based electrocardiogram (ECG) analysis tool (ECG Buddy) in a Korean population. This study investigated the performance of this tool in a US population, specifically assessing the left ventricular (LV) d...
Original Article 2025 August 13
Serum lactate to albumin ratio at hospital arrival and neurological outcome of out-of-hospital cardiac arrest: a nationwide multicenter observational study
Objective: We investigated the possible association between lower serum lactate to albumin ratio upon hospital arrival and out-of-hospital cardiac arrest (OHCA) outcome. Methods: Records from the Japanese Association for Acute Medicine–Out-of-Hospital Cardiac Arrest (JAAM-OHCA...
Original Article 2024 September 6
A rapid noninvasive wearable device for assessing cardiac troponin I level
Objective: Chest pain, a common emergency department presentation, requires rapid evaluation. The current gold standard of care is serial troponin measurements from blood draws along with an electrocardiogram and clinical presentation. However, an optical technology-based noninv...
Original Article 2025 January 14
Comparison of the efficacy of bolus low-dose ketamine versus bolus plus infusion low-dose ketamine on pain management in emergency departments: a randomized clinical trial
Objective: Ketamine is a promising drug for analgesia in emergency medicine, but the high rate of side effects is a barrier to widespread usage. We hypothesized that ketamine bolus followed by ketamine infusion would provide a more even and longer duration of analgesia and lower...
Original Article 2025 January 14
The long-term influences of age at injury on neuroinflammation and neuronal apoptosis following traumatic brain injury in pediatric and adult mice
Objective: The study explores the long-term impacts of traumatic brain injury (TBI) on neuroinflammation and neuronal apoptosis in pediatric and adult mice, focusing on how age at injury influences these processes. Methods: Controlled cortical impacts were used to induce TBI in...
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Current Issue
Volume 12(3); Sep 2025
Original Article
Critical Care
Comparison of Four Non-invasive Tools for Predicting Sepsis and Septic Shock Mortality: A Prospective Cohort Study
Matteo Guarino, Giacomo Maroncelli, Benedetta Perna, Paolo Baldin, Caterina Ghirardi, Alex Zanotto, Silvia Eichner, Matteo Bolognesi, Chiara Pesci, Martina Maritati, Carlo Contini, Roberto De Giorgio, Michele Domenico Spampinato
Received April 9, 2025     Accepted August 9, 2025     Published online December 2, 2025
DOI: https://doi.org/10.15441/ceem.25.075    
[Accepted]
      
Original Article
Digital health & Informatics
Automated Evaluation Framework for AI-Generated Emergency Department Documentation: A Chain-of-Thought Validation Study
Dasol Choi, Junhyuk Seo, Won Cul Cha, Minha Kim, Sejin Heo, Hansol Chang, Taerim Kim
Received July 15, 2025     Accepted August 31, 2025     Published online December 2, 2025
DOI: https://doi.org/10.15441/ceem.25.153    
[Accepted]
      
Original Article
Toxicology
Association of acute opioid-induced euphoria and analgesia with subsequent opioid prescriptions in an ED-based prospective cohort study
Spencer Brown, Eddie Irizarry, Andrew Williams, Michelle Davitt, Jesse Baer, Benjamin W. Friedman
Received March 5, 2025     Accepted July 29, 2025     Published online December 2, 2025
DOI: https://doi.org/10.15441/ceem.25.056    
[Accepted]
      
Original Article
Research Perspectives
Global academic productivity for emergency medicine and the research output by countries of different income levels
Alexei A. Birkun
Received June 28, 2025     Accepted August 3, 2025     Published online December 2, 2025
DOI: https://doi.org/10.15441/ceem.25.144    
[Accepted]
      
Original Article
Public Health & Policy
Pilot Study of Recurrent Abdominal Pain in the ED: Low-Risk Disease Associated with High Severity Pain and Frequent Opioid Administration
Soroush Shahamatdar, Felice Yang, Meylakh Barshay, Ryan Heidish, Aditya Loganathan, Taylor Bolden, William Huang, Andrew C. Meltzer
Received February 8, 2025     Accepted June 16, 2025     Published online December 2, 2025
DOI: https://doi.org/10.15441/ceem.25.036    
[Accepted]
      
Original Article
Airway
The Most Common Airway Foreign Bodies Removed with an Anti-Choking Suction Device: A Descriptive Retrospective Study
Špela Metličar, Gregor Štiglic, Nino Fijačko
Received May 25, 2025     Accepted August 27, 2025     Published online December 2, 2025
DOI: https://doi.org/10.15441/ceem.25.105    
[Accepted]
      
Brief Research Report
Public Health & Policy
Pilot Study Measuring Patient Reported Outcomes in Cannabinoid Hyperemesis Syndrome (CHS) patients treated in the Emergency Department
Ryan Heidish, Aditya Loganathan, Taylor Bolden, Ziva Cooper, Meylakh Barshay, Isabella Lagunzad, Andrew C. Meltzer
Received February 4, 2025     Accepted June 8, 2025     Published online December 2, 2025
DOI: https://doi.org/10.15441/ceem.25.032    
[Accepted]
      
Original Article
Trauma
Predictors of Intracranial Lesions in Patients with Traumatic Facial Fractures: Findings Derived from the National Trauma Registry of Iran
Zahra Ramezani, Payman Salamati, Vali Baigi, Vafa Rahimi-Movaghar, Mohammadreza Zafarghandi, Esmaeil Fakharian, Seyed Houssein Saeed-Banadaky, Yousef Mohammadpour, Seyed Mohammad Piri, Sara Mirzamohamadi, Khatereh Naghdi, Marjan Laal
Received January 26, 2025     Accepted June 9, 2025     Published online December 2, 2025
DOI: https://doi.org/10.15441/ceem.25.030    
[Accepted]
      
Review Article
Digital health & Informatics, Ethics
Ethical considerations of artificial intelligence in emergency medicine for triage and resource allocation: a scoping review
Hyunjae Cha, Junhewk Kim
Received August 31, 2025     Accepted September 23, 2025     Published online September 24, 2025
DOI: https://doi.org/10.15441/ceem.25.199    
[Accepted]
      
Original Article
Trauma
Skull fractures may be associated with hyperfibrinolysis in patients with isolated traumatic brain injury
Gaku Fujiwara, Naoto Shiomi
Received October 23, 2024     Accepted March 18, 2025     Published online August 13, 2025
DOI: https://doi.org/10.15441/ceem.24.344    
[Accepted]
      
Systematic Review
Pain Management & Sedation
Ketorolac analgesia in the emergency department in adults: systematic review and meta-analysis
Antimo Tessitore, Luisa Zupin, Fulvio Celsi, Valeria Capaci, Alessandro Amaddeo, Egidio Barbi, Giorgio Cozzi
Received January 2, 2025     Accepted July 12, 2025     Published online August 13, 2025
DOI: https://doi.org/10.15441/ceem.25.002    
[Accepted]
      
Review Article
Toxicology
The Role of Fomepizole in Acetaminophen-related Poisoning: A Narrative Review
Frank Chen, Shelly ZQ Lu, Harleen Choha, Anthony Lau
Received March 11, 2025     Accepted May 7, 2025     Published online August 13, 2025
DOI: https://doi.org/10.15441/ceem.25.059    
[Accepted]
      
Systematic Review
Airway
Efficacy of ketamine versus etomidate for rapid sequence intubation of critically ill patients in terms of mortality and success rate: a systematic review and meta-analysis of randomized controlled trials
Anjishnujit Bandyopadhyay, Partha Haldar, Chhavi Sawhney, Abhishek Singh
Received December 4, 2024     Accepted April 10, 2025     Published online August 13, 2025
DOI: https://doi.org/10.15441/ceem.24.363    
[Accepted]
         Crossref 1
Original Article
Cardiovascular
Comparison of regional wall motion abnormalities in patients with occlusion myocardial infarction with and without ST-elevation myocardial infarction (STEMI)
Alexander Bracey, H. Pendell Meyers, Caleb Watkins, Gautam R. Shroff, Daniel Lee, Adam Singer J., Stephen W. Smith
Received December 18, 2024     Accepted February 14, 2025     Published online August 13, 2025
DOI: https://doi.org/10.15441/ceem.24.373    
[Accepted]
         Crossref 2
Original Article
Pediatrics
Epidemiologic Trends in Pediatric Urinary Tract Infections Among United States Emergency Departments from 2016-2023
Michael Gottlieb, Tamara Amponsah, Nhat Nguyen, Ohm Shukla, Kyle Bernard, Eric Moyer
Received March 4, 2025     Accepted April 23, 2025     Published online April 30, 2025
DOI: https://doi.org/10.15441/ceem.25.055    
[Accepted]
      
Original Article
Emergency Medical Services
Oral anticoagulant use by emergency medical services in the United States
Henry E. Wang, Mengda Yu, Ching Min Chu, Travis P. Sharkey-Toppen, J. Madison Hyer, Michelle Nassal, Alix Delamare, Jonathan Powell, Lai Wei, Robert Lowe, Kim Moeller, Alexander Keister, Ashish Panchal
Received December 11, 2024     Accepted April 22, 2025     Published online April 30, 2025
DOI: https://doi.org/10.15441/ceem.24.369    
[Accepted]
      
Original Article
Pediatrics, Environmental
Characteristics of pediatric patients with heat-related illness transferred to emergency departments: descriptive analysis from Japan
Yohei Okada, Marcus Eng Hock Ong, Tadashi Ishihara, Shoji Yokobori, Jun Kanda
Received October 22, 2024     Accepted January 8, 2025     Published online April 30, 2025
DOI: https://doi.org/10.15441/ceem.24.343    
[Accepted]
      
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